Criteria for diagnosis of familial amyotrophic lateral sclerosis. European FALS Collaborative Group

Neuromuscul Disord. 1992;2(1):7-9. doi: 10.1016/0960-8966(92)90020-7.


Clinical criteria for the diagnosis of motor neuron disease, agreed at the inaugural meeting of the European Familial Amyotrophic Lateral Sclerosis Collaborative Group, are described. The criteria are derived from those developed for the study of sporadic amyotrophic lateral sclerosis, and allow the inclusion of certain recognized clinical sub-types of familial amyotrophic lateral sclerosis. They will require testing for consistency and sensitivity.

Publication types

  • Guideline
  • Practice Guideline
  • Review

MeSH terms

  • Amyotrophic Lateral Sclerosis / classification
  • Amyotrophic Lateral Sclerosis / diagnosis*
  • Amyotrophic Lateral Sclerosis / genetics
  • Humans