The sex-peptide

Bioessays. 1992 Nov;14(11):779-84. doi: 10.1002/bies.950141111.

Abstract

Injection of a peptide of 36 amino acids into virgin Drosophila females changes their reproductive properties drastically: males are rejected and egg laying is increased. The neuronal and physiological properties of the virgin state are replaced by a new pattern of behavior and stimulation of egg production and deposition. Under natural conditions, the peptide is synthesized by the male and transferred into the female during copulation. The sex-peptide, therefore, can be considered as a pheromone. In this review, I shall limit my discussion to Drosophila melanogaster.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Animals, Genetically Modified
  • Copulation / drug effects
  • Copulation / physiology
  • Drosophila Proteins*
  • Drosophila melanogaster / physiology*
  • Drosophila melanogaster / ultrastructure
  • Female
  • Genitalia, Male / metabolism
  • Genitalia, Male / ultrastructure
  • Insecta / physiology
  • Intercellular Signaling Peptides and Proteins
  • Male
  • Molecular Sequence Data
  • Oviposition / drug effects
  • Oviposition / physiology
  • Peptides / pharmacology
  • Peptides / physiology*
  • Recombinant Fusion Proteins / biosynthesis
  • Sexual Behavior, Animal / drug effects
  • Sexual Behavior, Animal / physiology*
  • Species Specificity

Substances

  • Acp36DE protein, Drosophila
  • Drosophila Proteins
  • Intercellular Signaling Peptides and Proteins
  • Peptides
  • Recombinant Fusion Proteins
  • SP protein, Drosophila
  • male accessory gland peptide, Drosophila