Antigen delivery systems for analysing host immune responses and for vaccine development

Trends Biotechnol. 1990 Sep;8(9):237-40. doi: 10.1016/0167-7799(90)90184-y.


Overall, the meeting was timely and worthwhile. It is evident that there is a need for comparative studies to establish a firm foundation for future work. This is particularly important since it appears that the responses observed are influenced by the particular strain used for attenuation, the means of attenuation, the antigen-presentation system employed and the animal most immunized. In this last regard, one must recognize that most work to date has been with inbred strains of mice which differ from the genetic diversity of most hosts that are the intended beneficiaries of the immunization strategies being developed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Bacterial / biosynthesis*
  • Antibodies, Bacterial / immunology
  • Antigens, Bacterial / administration & dosage
  • Antigens, Bacterial / immunology
  • Bacteria / pathogenicity
  • Bacterial Vaccines / administration & dosage
  • Bacterial Vaccines / immunology*
  • Humans
  • Immunization
  • Vaccines, Synthetic / administration & dosage
  • Vaccines, Synthetic / immunology*


  • Antibodies, Bacterial
  • Antigens, Bacterial
  • Bacterial Vaccines
  • Vaccines, Synthetic