Reversal of radiation-induced neutropenia by granulocyte colony-stimulating factor

Med Pediatr Oncol. 1992;20(3):240-2. doi: 10.1002/mpo.2950200312.


Myelosuppression is a common sequelae of radiotherapy, occasionally delaying the completion of treatment. In this report, we describe successful reversal of radiation-induced neutropenia in a child receiving craniospinal irradiation by granulocyte colony-stimulating factor (G-CSF). We suggest that G-CSF be considered as supportive care in patients in whom neutropenia develops during radiotherapy.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cerebellar Neoplasms / radiotherapy
  • Granulocyte Colony-Stimulating Factor / therapeutic use*
  • Humans
  • Infant
  • Male
  • Medulloblastoma / radiotherapy
  • Neutropenia / drug therapy*
  • Neutropenia / etiology
  • Radiotherapy / adverse effects


  • Granulocyte Colony-Stimulating Factor