Borna disease virus-specific antigens. II. The soluble antigen is a protein complex

I Bause-Niedrig; M Jackson; E Schein; H Ludwig; G Pauli

doi:10.1016/0165-2427(92)90022-i

Borna disease virus-specific antigens. II. The soluble antigen is a protein complex

Vet Immunol Immunopathol. 1992 Mar;31(3-4):361-9. doi: 10.1016/0165-2427(92)90022-i.

Authors

I Bause-Niedrig¹, M Jackson, E Schein, H Ludwig, G Pauli

Affiliation

¹ Institut für Virologie, Freien Universität Berlin, Germany.

PMID: 1375406
DOI: 10.1016/0165-2427(92)90022-i

Abstract

Borna disease virus-specific soluble antigen from persistently infected rat brains was purified to homogeneity using preparative sodium dodecyl sulphate-polyacrylamide gel electrophoresis. The soluble antigen is a complex of three proteins with apparent molecular weights of 35 kDa, 38 kDa and 24 kDa. The 35/38 kDa antigen double band was separated into its two components. The 24 kDa protein has no common epitopes with the 35/38 kDa protein.

MeSH terms

Animals
Antigens, Viral / immunology*
Antigens, Viral / isolation & purification
Borna disease virus / growth & development
Borna disease virus / immunology*
Brain / microbiology
Chromatography, High Pressure Liquid
Electrophoresis, Polyacrylamide Gel
Epitopes / immunology
Molecular Weight
Rats
Solubility
Viral Proteins / immunology*
Viral Proteins / isolation & purification

Substances

Antigens, Viral
Epitopes
Viral Proteins