The effect of short-term fasting and a single meal on protein synthesis and oxygen consumption in cod, Gadus morhua

J Comp Physiol B. 1992;162(3):209-15. doi: 10.1007/BF00357525.

Abstract

Rates of protein synthesis and oxygen consumption (MO2) in cod were compared in both fasted and refed animals. During a 14-day fast both protein synthesis and respiration rates fell to stable values after 6 days. When a meal of whole sandeel at 6% body weight was fed to fish fasted for 6 days, protein synthesis and MO2 increased to a maximum at between 12 and 18 h after feeding. Peak MO2 was about twice the pre-feeding values, while whole animal protein synthesis increased four-fold. There were differences between tissues in the timing of maximum protein synthesis; the liver and stomach responded faster than the remainder of the body. Maximum protein synthesis rates in the liver and stomach occurred at 6 h after feeding, at which time their calculated contribution to total MO2 was 11%. Similar calculations suggested that the integrated increment in whole animal protein synthesis contributed between 23% and 44% of the post-prandial increase in MO2. It was concluded that protein synthesis is an important contributor to increased MO2 after feeding in cod.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Eating / physiology
  • Fasting / metabolism
  • Fishes / metabolism*
  • Kinetics
  • Oxygen Consumption*
  • Protein Biosynthesis*
  • RNA / metabolism
  • Tissue Distribution

Substances

  • RNA