Chromosomal localisation of the mouse and human peripherin genes

Genet Res. 1992 Apr;59(2):125-9. doi: 10.1017/s0016672300030330.


Using a mouse cDNA probe encoding for the major part of peripherin, a type III intermediate filament protein, we have assigned, by in situ hybridization, the mouse and human peripherin genes, Prph, to the E-F region of chromosome 15 and to the q12-q13 region of chromosome 12, respectively. These regions are known as homologous chromosomal segments containing other intermediate filament genes (keratins) and also other genes which could be co-ordinately regulated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromosomes
  • DNA / genetics
  • Genes
  • Humans
  • Intermediate Filament Proteins / genetics*
  • Keratins / genetics
  • Membrane Glycoproteins*
  • Mice
  • Nerve Tissue Proteins*
  • Nucleic Acid Hybridization
  • Peripherins


  • Intermediate Filament Proteins
  • Membrane Glycoproteins
  • Nerve Tissue Proteins
  • PRPH protein, human
  • Peripherins
  • Prph protein, mouse
  • Keratins
  • DNA