Abstract
TAPA-1 is a member of a new family of evolutionarily conserved transmembrane proteins which may be involved in regulation of cell growth and/or cell signalling. We have examined the temporal pattern of TAPA-1 RNA expression during mouse development. Using a sensitive reverse transcription/polymerase chain reaction assay, we show that TAPA-1 RNA is present in oocytes, fertilized eggs and cleavage stage embryos.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Antigens, CD*
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Antigens, Surface / biosynthesis
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Antigens, Surface / genetics*
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Base Sequence
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Blastocyst / physiology*
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Blotting, Northern
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Female
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Membrane Proteins / genetics*
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Mice
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Mice, Inbred Strains
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Molecular Sequence Data
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Oligodeoxyribonucleotides
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Oocytes / physiology
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Polymerase Chain Reaction / methods
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Protein Conformation
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RNA / genetics
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RNA / isolation & purification
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RNA-Directed DNA Polymerase / metabolism
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Stem Cells / physiology
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Tetraspanin 28
Substances
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Antigens, CD
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Antigens, Surface
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Cd81 protein, mouse
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Membrane Proteins
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Oligodeoxyribonucleotides
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Tetraspanin 28
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RNA
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RNA-Directed DNA Polymerase