Expression of TAPA-1 in preimplantation mouse embryos

Biochem Biophys Res Commun. 1992 Aug 14;186(3):1201-6. doi: 10.1016/s0006-291x(05)81533-5.

Abstract

TAPA-1 is a member of a new family of evolutionarily conserved transmembrane proteins which may be involved in regulation of cell growth and/or cell signalling. We have examined the temporal pattern of TAPA-1 RNA expression during mouse development. Using a sensitive reverse transcription/polymerase chain reaction assay, we show that TAPA-1 RNA is present in oocytes, fertilized eggs and cleavage stage embryos.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antigens, CD*
  • Antigens, Surface / biosynthesis
  • Antigens, Surface / genetics*
  • Base Sequence
  • Blastocyst / physiology*
  • Blotting, Northern
  • Female
  • Membrane Proteins / genetics*
  • Mice
  • Mice, Inbred Strains
  • Molecular Sequence Data
  • Oligodeoxyribonucleotides
  • Oocytes / physiology
  • Polymerase Chain Reaction / methods
  • Protein Conformation
  • RNA / genetics
  • RNA / isolation & purification
  • RNA-Directed DNA Polymerase / metabolism
  • Stem Cells / physiology
  • Tetraspanin 28

Substances

  • Antigens, CD
  • Antigens, Surface
  • Cd81 protein, mouse
  • Membrane Proteins
  • Oligodeoxyribonucleotides
  • Tetraspanin 28
  • RNA
  • RNA-Directed DNA Polymerase