Abstract
Further sequencing of a cDNA encoding the C-terminal region of a rat intestinal mucin peptide reveals a region corresponding to 258 amino acids enriched in serine, threonine and proline, but no typical mucin-like tandem repeat structures. Between this region and a previously described stretch of 4.5 degenerate S,T,P-rich tandem repeats, there is a 42 amino acid cysteine-rich segment. The discontinuity of cysteine-rich and S,T,P-rich areas near the C-terminus has not been observed in other mammalian mucin structures reported to date.
Publication types
-
Comparative Study
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Amino Acid Sequence
-
Animals
-
Base Sequence
-
Blotting, Northern
-
DNA / genetics
-
DNA / isolation & purification
-
Intestinal Mucosa / physiology*
-
Molecular Sequence Data
-
Mucins / genetics*
-
Proline*
-
RNA / genetics
-
RNA / isolation & purification
-
RNA, Messenger / genetics
-
Rats
-
Repetitive Sequences, Nucleic Acid
-
Restriction Mapping
-
Sequence Homology, Nucleic Acid
-
Serine*
-
Threonine*
Substances
-
Mucins
-
RNA, Messenger
-
mucin-like peptide 3500
-
Threonine
-
Serine
-
RNA
-
DNA
-
Proline
Associated data
-
GENBANK/L07316
-
GENBANK/M91429
-
GENBANK/M91430
-
GENBANK/M93297
-
GENBANK/M93298
-
GENBANK/M93299
-
GENBANK/M93300
-
GENBANK/M93301
-
GENBANK/M94056
-
GENBANK/Z11875