Binding of laminin, type IV collagen, and vitronectin by Streptococcus pneumoniae

Zentralbl Bakteriol. 1992 Jun;277(1):80-3. doi: 10.1016/s0934-8840(11)80874-1.

Abstract

Forty-three strains of Streptococcus pneumoniae were tested for their ability to bind radiolabelled laminin, collagen types I, II and IV, fibronectin, and vitronectin. Two basement membrane components, laminin and type IV collagen, interacted with many S. pneumoniae strains. All strains bound laminin and 28 (65%) bound collagen type IV. Approximately 60% of the strains bound vitronectin but only a few strains showed low binding of fibronectin and collagen type I and II.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Adhesion*
  • Collagen / chemistry*
  • Glycoproteins / chemistry*
  • Laminin / chemistry*
  • Protein Binding
  • Streptococcal Infections / microbiology
  • Streptococcus pneumoniae / physiology*
  • Vitronectin

Substances

  • Glycoproteins
  • Laminin
  • Vitronectin
  • Collagen