Nitric oxide as a secretory product of mammalian cells

FASEB J. 1992 Sep;6(12):3051-64.


Evolution has resorted to nitric oxide (NO), a tiny, reactive radical gas, to mediate both servoregulatory and cytotoxic functions. This article reviews how different forms of nitric oxide synthase help confer specificity and diversity on the effects of this remarkable signaling molecule.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amino Acid Oxidoreductases / antagonists & inhibitors
  • Amino Acid Oxidoreductases / metabolism
  • Animals
  • Humans
  • Nitric Oxide / metabolism*
  • Nitric Oxide Synthase
  • Terminology as Topic


  • Nitric Oxide
  • Nitric Oxide Synthase
  • Amino Acid Oxidoreductases