[Mercury concentration in blood and urine--before and after the placement of dental amalgam fillings]

Zentralbl Hyg Umweltmed. 1992 Aug;193(2):175-87.
[Article in German]


70 patients of dentist's surgery were given MOD amalgam fillings (non-gamma-2 amalgam) for molars. They were allocated for comparison to four groups defined by their treatment, i.e. the number of old and new restorations and whether a rubber dam was used. Blood and urine samples were collected at regular intervals before and during a 14-day period after treatment and tested for mercury concentration (Hg). Over the observation period the groups with the highest exposure (1-2 old restorations replaced by new ones) showed a tendency, in contrast to the less exposed groups (1 new filling with or without dam), towards increases (p less than 0.10) in group average Hg values of approx. 0.2 microgram/L (blood) and 0.3 microgram/g creatinine (urine) as acute treatment effects. The highest values recorded before and after the treatment, 3.3 micrograms/L (blood) and 16.5 micrograms/L (urine) are higher than normal but do not indicate any increase in the risk to health especially if they are not persistent.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Creatinine / urine
  • Dental Amalgam*
  • Dental Restoration, Permanent*
  • Female
  • Humans
  • Male
  • Mercury / blood*
  • Mercury / urine
  • Risk Factors


  • Dental Amalgam
  • Creatinine
  • Mercury