Ventilatory dysfunction in severe anorexia nervosa

Chest. 1992 Oct;102(4):1286-8. doi: 10.1378/chest.102.4.1286.


A 25-year-old woman suffering from chronic anorexia nervosa lost more than 50 percent of her body weight and presented with generalized muscle weakness. Pulmonary function tests showed a severe restrictive defect, and she had marked impairment of respiratory muscle strength and endurance, peripheral muscle function, and hypercapnic ventilatory responses, all of which improved following refeeding. The interaction and response to treatment of these effects on respiratory function are discussed.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anorexia Nervosa / complications*
  • Female
  • Humans
  • Nutrition Disorders / complications
  • Nutrition Disorders / physiopathology
  • Respiration Disorders / etiology*
  • Respiration Disorders / physiopathology
  • Respiratory Mechanics
  • Respiratory Muscles / physiopathology