Genetic and cell biological aspects of the yeast vacuolar H(+)-ATPase

Y Anraku; N Umemoto; R Hirata; Y Ohya

doi:10.1007/BF00762532

Genetic and cell biological aspects of the yeast vacuolar H(+)-ATPase

J Bioenerg Biomembr. 1992 Aug;24(4):395-405. doi: 10.1007/BF00762532.

Authors

Y Anraku¹, N Umemoto, R Hirata, Y Ohya

Affiliation

¹ Department of Biology, Faculty of Science, University of Tokyo, Japan.

PMID: 1400284
DOI: 10.1007/BF00762532

Abstract

The yeast vacuolar proton-translocating ATPase is a member of the third class of H(+)-pumping ATPase. A family of this type of H(+)-ATPase is now known to be ubiquitously distributed in eukaryotic vacuo-lysosomal organelles and archaebacteria. Nine VMA genes that are indispensable for expression of the enzyme activity have been cloned and characterized in the yeast Saccharomyces cerevisiae. This review summarizes currently available information on the VMA genes and cell biological functions of the VMA gene products.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Proton-Translocating ATPases / genetics
Proton-Translocating ATPases / physiology*
Saccharomyces cerevisiae / enzymology*
Vacuoles / enzymology

Substances

Proton-Translocating ATPases