N-(1-oxododecyl)-4 alpha,10-dimethyl-8-aza-trans-decal-3 Beta-Ol: A Potent Competitive Inhibitor of 2,3-oxidosqualene Cyclase

J Med Chem. 1992 Sep 18;35(19):3581-3. doi: 10.1021/jm00097a017.

MeSH terms

  • Cells, Cultured
  • Enzyme Inhibitors / chemical synthesis*
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology
  • Intramolecular Transferases*
  • Isomerases / antagonists & inhibitors*
  • Isoquinolines / chemical synthesis
  • Isoquinolines / chemistry
  • Isoquinolines / pharmacology

Substances

  • Enzyme Inhibitors
  • Isoquinolines
  • N-(1-oxododecyl)-4,10-dimethyl-8-azadecal-3-ol
  • Isomerases
  • Intramolecular Transferases
  • lanosterol synthase