Peyronie's disease is often managed surgically when medical management fails and sexual function is impaired due to residual curvature or loss of erectile function. In this study 63 patients were treated surgically, with 25 receiving a penile prosthesis, 25 undergoing a tunica vaginalis graft and 13 undergoing the Nesbit ellipse procedure. The long-term surgical outcome as determined by sexual function indicated that the penile prosthesis group remained the most sexually active, followed by the Nesbit ellipse group with the tunica vaginalis graft group being the least sexually active. Incision of curvature with placement of a penile prosthesis for the surgical management of Peyronie's disease remains an approach that has excellent long-term functional results.