Chorea gravidarum and chorea associated with oral contraceptives--diseases due to antiphospholipid antibodies?

Acta Neurol Scand. 1992 Aug;86(2):219-20. doi: 10.1111/j.1600-0404.1992.tb05070.x.

Abstract

A woman with chorea gravidarum in the absence of SLE is described. She later developed severe chorea while using the contraceptive pill, and high titered antiphospholipid antibodies were detected in serum. A rapid recovery after high dose i.v. methylprednisolone was observed. Deterioration occurred in a later pregnancy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antiphospholipid Syndrome / etiology*
  • Chorea / etiology*
  • Contraceptives, Oral, Synthetic / administration & dosage
  • Contraceptives, Oral, Synthetic / adverse effects*
  • Desogestrel / administration & dosage
  • Desogestrel / adverse effects*
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Neurologic Examination
  • Pregnancy
  • Pregnancy Complications / etiology*
  • Risk Factors

Substances

  • Contraceptives, Oral, Synthetic
  • Desogestrel