[Effect of sodium 18 beta-glycyrrhetate on experimental arrhythmia]

X Li; Y Wu; Z Guo; L Liu

[Effect of sodium 18 beta-glycyrrhetate on experimental arrhythmia]

Zhongguo Zhong Yao Za Zhi. 1992 Mar;17(3):176-8, inside backcover.

[Article in Chinese]

Authors

X Li¹, Y Wu, Z Guo, L Liu

Affiliation

¹ Department of Pharmacology, Lanzhou Medical College.

PMID: 1418542

Abstract

The effect of sodium 18 beta-glycyrrhetate (SGA) on experimental arrhythmia was investigated. The result shows that SGA strongly counteracts arrhythmia induced by chloroform of chloroform adrenaline, lengthens the appearance time of arrhythmia induced by CaCl2, slightly retards the heart rate of rats and rabbits, and partly antagonizes the acceleration effect of isoproterenol on rabbit hearts.

Publication types

English Abstract

MeSH terms

Animals
Anti-Arrhythmia Agents / pharmacology*
Anti-Arrhythmia Agents / therapeutic use
Aorta
Arrhythmias, Cardiac / drug therapy*
Female
Glycyrrhetinic Acid / pharmacology*
Glycyrrhetinic Acid / therapeutic use
Heart Rate / drug effects
Male
Mice
Muscle Contraction / drug effects
Muscle, Smooth, Vascular / drug effects
Rabbits
Ventricular Fibrillation / prevention & control

Substances

Anti-Arrhythmia Agents
Glycyrrhetinic Acid