Abstract
Extraordinary progress has been made in refining our understanding of the B-cell antigen receptor complex, the role of protein-tyrosine phosphorylation as the key intermediary in immunoglobulin signal transduction, and in identifying candidate effectors of immunoglobulin-mediated signaling. In addition, the properties of a new group of G proteins may rekindle interest in older observations implicating such molecules as important in B-cell activation.
Publication types
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, P.H.S.
-
Review
MeSH terms
-
Amino Acid Sequence
-
Animals
-
B-Lymphocytes / physiology*
-
GTP-Binding Proteins / physiology
-
Humans
-
Lymphocyte Activation / physiology*
-
Molecular Sequence Data
-
Phosphorylation
-
Protein-Tyrosine Kinases / physiology
-
Receptors, Antigen, B-Cell / physiology
-
Signal Transduction / physiology
-
Tyrosine / physiology
Substances
-
Receptors, Antigen, B-Cell
-
Tyrosine
-
Protein-Tyrosine Kinases
-
GTP-Binding Proteins