Curr Opin Immunol. 1992 Jun;4(3):314-20. doi: 10.1016/0952-7915(92)90082-p.


Despite the short history of interleukin-10, accumulated evidence indicates that this interleukin plays a major role in suppressing immune and inflammatory responses. Yet interleukin-10 also maintains cell viability and acts as a cofactor to promote the growth of lymphoid and myeloid cells in vitro. Here we review the present knowledge on the structure and function of interleukin-10.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • B-Lymphocytes / immunology
  • Humans
  • Interleukin-10 / physiology*
  • Killer Cells, Natural / immunology
  • Lymphocyte Activation
  • Macrophages / immunology
  • Mast Cells / immunology
  • Monocytes / immunology
  • T-Lymphocytes / immunology


  • Interleukin-10