Molecular linkage between cadherins and actin filaments in cell-cell adherens junctions

Curr Opin Cell Biol. 1992 Oct;4(5):834-9. doi: 10.1016/0955-0674(92)90108-o.


The cell-cell adherens junction is a site for cadherin-mediated cell adhesion where actin filaments are densely associated with the plasma membrane through its well-developed plasmalemmal undercoat. Recent research has focused on the molecular linkage between cadherins and actin filaments in the undercoat of adherens junctions in order to understand the functions of these undercoat-constitutive proteins in the regulation and signal transduction of cadherin-based cell adhesion.

Publication types

  • Review

MeSH terms

  • Actins / metabolism*
  • Animals
  • Cadherins / metabolism*
  • Cell Adhesion*
  • Humans
  • Intercellular Junctions / metabolism*


  • Actins
  • Cadherins