The management of a case of treatment-resistant paraphilia with a long-acting LHRH agonist

Can J Psychiatry. 1992 Oct;37(8):567-9. doi: 10.1177/070674379203700808.

Abstract

A patient with multiple paraphilias who had been treated for several years with sex drive reducing agents (cyproterone acetate and medroxyprogesterone acetate) with little effect on sexual activity or fantasy was offered treatment with long-acting leuprolide acetate, on LHRH agonist. This produced a marked decrease in all reported sexual thoughts and activities with no significant side-effects.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Delayed-Action Preparations
  • Humans
  • Injections, Subcutaneous
  • Leuprolide / administration & dosage*
  • Libido / drug effects
  • Libido / physiology
  • Luteinizing Hormone / blood
  • Male
  • Paraphilic Disorders / blood
  • Paraphilic Disorders / drug therapy*
  • Paraphilic Disorders / psychology
  • Pedophilia / blood
  • Pedophilia / drug therapy*
  • Pedophilia / psychology
  • Prolactin / blood
  • Testosterone / blood

Substances

  • Delayed-Action Preparations
  • Testosterone
  • Prolactin
  • Luteinizing Hormone
  • Leuprolide