Defects in a Cell Cycle Checkpoint May Be Responsible for the Genomic Instability of Cancer Cells

Cell. 1992 Nov 13;71(4):543-6. doi: 10.1016/0092-8674(92)90586-2.

Author

L Hartwell¹

Affiliation

¹ Department of Genetics, University of Washington, Seattle 98195.

PMID: 1423612
DOI: 10.1016/0092-8674(92)90586-2

Publication types

Review

MeSH terms

Cell Cycle / genetics*
Cell Transformation, Neoplastic / genetics*
Gene Amplification / genetics
Genes, p53 / genetics*
Humans
Mutation / genetics
Neoplasms / genetics*