Evaluation of a latex test for rapid detection of pneumococcal antigens in sputum

Eur J Clin Microbiol Infect Dis. 1992 May;11(5):448-51. doi: 10.1007/BF01961861.


A latex agglutination test (Directigen) for detection of pneumococcal capsular polysaccharide antigens in sputum was evaluated in comparison to culture and Gram stain using 121 sputum specimens. The sensitivity, specificity and rate of agreement of the latex test compared to culture were 90%, 79% and 81%, respectively. The results suggest that the latex test may be useful for detecting pneumococcal antigen in sputum.

Publication types

  • Comparative Study

MeSH terms

  • Bacterial Capsules / analysis*
  • Evaluation Studies as Topic
  • Humans
  • Latex Fixation Tests*
  • Pneumococcal Infections / diagnosis*
  • Pneumococcal Infections / immunology
  • Sensitivity and Specificity
  • Sputum / immunology
  • Sputum / microbiology*
  • Streptococcus pneumoniae / immunology
  • Streptococcus pneumoniae / isolation & purification*