MYELOMA PROTEINS AND THE CLINICAL RESPONSE TO MELPHALAN THERAPY

Science. 1965 Apr 16;148(3668):376-7. doi: 10.1126/science.148.3668.376.

Abstract

Objective improvement after therapy with melphalan occurred in all patients producing only Bence Jones kappa proteins, in half of the patients with myeloma serum proteins, and in none of those producing only Bence Jones lambda proteins.

MeSH terms

  • Bence Jones Protein*
  • Blood Proteins*
  • Drug Therapy*
  • Humans
  • Leukopenia*
  • Melphalan*
  • Multiple Myeloma*
  • Myeloma Proteins*
  • Neoplasms / epidemiology*
  • Prognosis
  • Toxicology*

Substances

  • Blood Proteins
  • Myeloma Proteins
  • Bence Jones Protein
  • Melphalan