Position-specific expression of the annulin protein during grasshopper embryogenesis

Dev Biol. 1992 Nov;154(1):129-42. doi: 10.1016/0012-1606(92)90054-k.

Abstract

Annulin, named for its annular expression in developing limb buds, is a approximately 100 kDa membrane-associated protein that is expressed in a complex and changing pattern during grasshopper embryogenesis. Its expression is dynamic along the developing midline and in the mesoderm, transient in neuroepithelial sheath cells around mitotic neuroblasts, and position-specific in circumferential stripes in each limb bud segment. Annulin expression begins along the midline of the embryo at the onset of gastrulation. Mesoderm cells express the protein as they migrate away from the midline as do new cells that come to lie at the midline. During neurogenesis, annulin expression disappears from many midline cells until only a specific subset of midline glial cells expresses high levels of the protein. Starting at the beginning of neurogenesis, sheath cells express annulin in correlation with the mitotic activity of the neuroblasts they surround.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Extremities / embryology
  • Gene Expression Regulation
  • Grasshoppers / embryology*
  • Membrane Proteins / analysis
  • Membrane Proteins / metabolism*
  • Mesoderm / metabolism
  • Neuroglia / metabolism*

Substances

  • Membrane Proteins
  • annulin