Management of aspirin-sensitive rhinosinusitis-asthma syndrome: what role for aspirin desensitization?

Allergy Proc. Jul-Aug 1992;13(4):175-84. doi: 10.2500/108854192778817202.


Although aspirin is only one of the triggers of asthma attacks in patients with aspirin-sensitive rhinosinusitis asthma, aspirin sensitivity heralds severe and protracted disease requiring comprehensive management of all components of the syndrome. A review of the literature on the management of patients with aspirin-sensitive rhinosinusitis-asthma allows for the establishment of guidelines for conducting aspirin desensitization and evaluating the clinical usefulness of this procedure.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Aspirin / administration & dosage
  • Aspirin / adverse effects*
  • Asthma / chemically induced*
  • Asthma / therapy
  • Chronic Disease
  • Desensitization, Immunologic*
  • Humans
  • Rhinitis, Allergic, Perennial / chemically induced*
  • Rhinitis, Allergic, Perennial / therapy
  • Sinusitis / chemically induced*
  • Sinusitis / therapy
  • Syndrome


  • Aspirin