The features of antimony excretion by sweat glands were studied in normal subjects and patients with chronic bronchitis, chronic gastritis, chronic nephritis and calculous pyelonephritis, visceral leishmaniasis, living in some biogeochemical provinces of Fergana Valley. A micromethod based on the coloured reaction of the element with brilliant green was worked out to detect antimony in sweat. Sweat antimony elimination was proved to play a significant role in health and disease. The workers engaged in antimony production, the inhabitants of antimony biogeochemical regions should have their sweat excretion tested to score the Sb level. It is recommended as an additional test for screening and controlling the effects of visceral leishmaniasis chemotherapy by solusurmine in patients with kidney disorders.