Leiomyosarcoma in dogs: 44 cases (1983-1988)

J Am Vet Med Assoc. 1992 Oct 1;201(7):1077-9.

Abstract

During a 5-year period, leiomyosarcoma was diagnosed in 57 dogs. Forty-four dogs were included in the study on the basis of completeness of medical records. All dogs underwent exploratory laparotomy, and dogs were allotted to 4 groups according to primary site of tumor: spleen (16 dogs, median age 10.3 years), stomach/small intestine (13 dogs, median age 10.3 years), cecum (10 dogs, median age 11.8 years), and liver (5 dogs, median age 9 years). All dogs with leiomyosarcoma of the liver had visible metastasis and were euthanatized at surgery. In the other 3 groups, 79% of the dogs had no gross evidence of metastasis at surgery, and 64% survived greater than 2 weeks. Median survival in these 3 groups was 10 months (range, 1 month to 7 years); 48% died of metastasis, 32% died of unrelated causes, and 16% died of unknown causes. The prognosis in dogs with leiomyosarcoma of the spleen, stomach, small intestine, and especially the cecum is good to excellent if surgery is performed. In dogs with leiomyosarcoma of the liver, the prognosis is poor.

MeSH terms

  • Animals
  • Cecal Neoplasms / surgery
  • Cecal Neoplasms / veterinary
  • Dog Diseases / surgery*
  • Dogs
  • Female
  • Gastrointestinal Neoplasms / surgery
  • Gastrointestinal Neoplasms / veterinary*
  • Intestinal Neoplasms / surgery
  • Intestinal Neoplasms / veterinary
  • Intestine, Small
  • Leiomyosarcoma / surgery
  • Leiomyosarcoma / veterinary*
  • Liver Neoplasms / surgery
  • Liver Neoplasms / veterinary*
  • Male
  • Prognosis
  • Retrospective Studies
  • Splenic Neoplasms / surgery
  • Splenic Neoplasms / veterinary*
  • Stomach Neoplasms / surgery
  • Stomach Neoplasms / veterinary
  • Treatment Outcome