We studied the feasibility of fixation of an intraocular lens in the posterior chamber by utilizing Dacron mesh to stimulate cellular ingrowth from the posterior iris surface. Tissue ingrowth into the Dacron mesh occurred five days after Dacron implantation and a firm adhesion between Dacron and the iris developed in a consistent and localized manner. Dacron fibers, when placed in contact with the posterior iris surface, induce fibroblastic and pigmented epithelial tissue ingrowth around the fibers. Fixation of the lens with and without the posterior lens capsule and vitreous is compared in vitrectomized and nonvitrectomized eyes. It is possible to achieve fixation without support from the posterior lens capsule and vitreous.