Sudden fetal death in women with well-controlled, intensively monitored gestational diabetes

J Perinatol. 1992 Sep;12(3):229-33.

Abstract

An intensive antepartum monitoring system for women with gestational diabetes mellitus was evaluated over a 5-year period. Early diagnosis and liberal treatment with insulin was concomitantly followed with non-stress testing: weekly from 28 to 34 weeks' gestation and semi-weekly thereafter. Despite maternal euglycemia and satisfactory antepartum assessment, three fetal deaths occurred within 72 hours of reassuring fetal monitoring. Additionally, 24 (7%) fetuses were delivered on the basis of a low biophysical profile score (less than 6) at term. The stillbirth rate for women with gestational diabetes was 7.7/1000, whereas the stillbirth rate for nondiabetic low-risk patients was 4.8/1000. Women with gestational diabetes continue to be in a high-risk category for antepartum fetal death, requiring intensive monitoring with consideration for timely delivery.

MeSH terms

  • Adult
  • Blood Glucose / analysis
  • Death, Sudden*
  • Diabetes Mellitus, Type 1 / blood
  • Diabetes, Gestational* / blood
  • False Negative Reactions
  • Female
  • Fetal Death*
  • Fetal Monitoring*
  • Humans
  • Pregnancy

Substances

  • Blood Glucose