Detection of serum antitrichomonal antibodies in urogenital trichomoniasis by immunofluorescence

J Postgrad Med. Apr-Jun 1992;38(2):72-4.

Abstract

Trichomonas vaginalis is a frequently encountered genital pathogen in both males and females. In females, vaginitis due to this parasite is one of the most common manifestation. The indirect fluorescent technique (IFA) test was carried out to detect antitrichomonal antibodies in 370 female patients using whole cell antigen. Seventy one (19.18%) gave positive reaction for either of the class IgG, IgM and IgA antibodies. The level of the IgG class antibodies was found to be higher i.e. 58 (81.69%) than IgM 11 (15.27%) antibodies, which may be suggestive of past infection or a prolonged manifestation by the organisms.

MeSH terms

  • Antibodies, Anti-Idiotypic / blood*
  • Evaluation Studies as Topic
  • Female
  • Fluorescent Antibody Technique / standards*
  • Hospitals, University
  • Humans
  • Immunoglobulin A / immunology*
  • Immunoglobulin G / immunology*
  • Immunoglobulin M / immunology*
  • India / epidemiology
  • Mass Screening
  • Outpatient Clinics, Hospital
  • Sensitivity and Specificity
  • Trichomonas Vaginitis / blood*
  • Trichomonas Vaginitis / epidemiology
  • Trichomonas Vaginitis / immunology

Substances

  • Antibodies, Anti-Idiotypic
  • Immunoglobulin A
  • Immunoglobulin G
  • Immunoglobulin M