Stable dye-DNA intercalation complexes as reagents for high-sensitivity fluorescence detection

A N Glazer; H S Rye

doi:10.1038/359859a0

Stable dye-DNA intercalation complexes as reagents for high-sensitivity fluorescence detection

Nature. 1992 Oct 29;359(6398):859-61. doi: 10.1038/359859a0.

Authors

A N Glazer¹, H S Rye

Affiliation

¹ Department of Molecular and Cell Biology, University of California, Berkeley 94720.

PMID: 1436062
DOI: 10.1038/359859a0

Abstract

Fluorescent intercalation complexes of certain polycationic ligands with double-stranded DNA provide a new class of multichromophore labels for fluorescence assays.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Base Sequence
DNA / analysis*
DNA / chemistry
Fluorescent Dyes*
Intercalating Agents*
Spectrometry, Fluorescence / methods

Substances

Fluorescent Dyes
Intercalating Agents
DNA