Sequence of a 12.7 kb segment of yeast chromosome II identifies a PDR-like gene and several new open reading frames

Yeast. 1992 Sep;8(9):761-8. doi: 10.1002/yea.320080909.

Abstract

A 12,684 bp DNA fragment, between FUS3 and the centromere, from the left arm of chromosome II of Saccharomyces cerevisiae was sequenced as part of the European project to sequence the whole chromosome. This segment contains at least five complete new open reading frames (ORFs) and the beginning (191 first 5' codons) of an ORF whose putative translational product is highly similar to the multidrug resistance PDR1 gene previously characterized by Balzi et al. (1987) on chromosome VII.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Chromosome Mapping
  • Chromosomes, Fungal
  • DNA, Fungal / genetics*
  • Drug Resistance, Microbial / genetics
  • Fungal Proteins / genetics
  • Genes, Fungal*
  • Molecular Sequence Data
  • Open Reading Frames
  • Protein Biosynthesis
  • Saccharomyces cerevisiae / genetics*
  • Sequence Homology, Amino Acid

Substances

  • DNA, Fungal
  • Fungal Proteins