Abstract
Oxidation of benzocyclobutene by intact cells of Pseudomonas fluorescens 127-68 XVII, containing naphthalene dioxygenase, yielded exclusively benzylic oxidation products; benzocyclobutene-1-ol and benzocyclobutene-1-one. No evidence for incorporation of oxygen into the aromatic ring was found.
MeSH terms
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Biotransformation
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Cyclobutanes / chemistry
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Cyclobutanes / pharmacokinetics*
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Dioxygenases
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Multienzyme Complexes / metabolism*
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Oxygenases / metabolism*
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Pseudomonas fluorescens / metabolism*
Substances
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Cyclobutanes
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Multienzyme Complexes
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Oxygenases
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Dioxygenases
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naphthalene dioxygenase