Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1992 Sep;42(9):1157-9.

In Vitro Activity of Taurolidine, Chlorophenol-Camphor-Menthol and Chlorhexidine Against Oral Pathogenic Microorganisms

Affiliations
  • PMID: 1445486
Comparative Study

In Vitro Activity of Taurolidine, Chlorophenol-Camphor-Menthol and Chlorhexidine Against Oral Pathogenic Microorganisms

M Zimmermann et al. Arzneimittelforschung. .

Abstract

The antimicrobial activity of taurolidine (Taurolin, CAS 19388-87-5), a synthetic broad-spectrum antimicrobial agent and anti-toxin, and two conventional antiseptics, chlorophenol-camphor-menthol (CCM) and chlorhexidine digluconate (CHX) were compared using the serial dilution test on 10 potential oral pathogenic bacterial species. The minimum inhibitory and minimum bactericidal concentrations were lowest for CHX (MIC 0.03-0.12 mg/ml), followed by taurolidine (MIC 0.12-0.5 mg/ml) and CCM (MIC 0.5-2.0 mg/ml). However, if both bacterial efficacy and cytotoxicity are considered, only taurolidine achieves extensive bactericidal activity with tissue tolerability.

Similar articles

See all similar articles

Cited by 4 articles

Publication types

MeSH terms

LinkOut - more resources

Feedback