Cerebral artery aneurysms in children infected with human immunodeficiency virus

J Pediatr. 1992 Dec;121(6):927-30. doi: 10.1016/s0022-3476(05)80344-0.


More than 250 children treated at our institution on antiretroviral treatment protocols have been monitored with brain imaging studies. We documented the occurrence and progression of aneurysms of major cerebral arteries in two children with advanced human immunodeficiency virus infection. In both cases these lesions remained clinically silent initially, despite progression to marked dilation.

Publication types

  • Case Reports

MeSH terms

  • Brain / pathology
  • Cerebral Angiography
  • Child
  • Didanosine / therapeutic use
  • Drug Therapy, Combination
  • HIV Infections / complications*
  • HIV Infections / drug therapy
  • HIV-1*
  • Humans
  • Intracranial Aneurysm / complications*
  • Intracranial Aneurysm / diagnosis
  • Magnetic Resonance Imaging
  • Male
  • Zidovudine / therapeutic use


  • Zidovudine
  • Didanosine