[Fertility preservation in early cervical cancer]

Gynecol Obstet Fertil. 2003 Sep;31(9):706-12. doi: 10.1016/s1297-9589(03)00200-5.
[Article in French]

Abstract

Objective: Evaluation of surgical techniques leading to fertility preservation in patients with early cervical cancer.

Patients and methods: Carcinological and obstetrical follow-up of 95 patients treated with radical trachelectomy between 1987 and 2002 for a cervical cancer stage less than Ib2.

Results: Four recurrences were observed; all of these were in case of tumor more than 2 cm in diameter (P = 0.002), and three of the four recurrences were in case of lymph-vascular space involvement (P = 0.07). Among the 42 patients willing and able to procreate, 33 were pregnant. Fifty-six pregnancies were registered. The rate of late miscarriage was 19% and 34 living newborns were obtained.

Conclusion: In case of early cervical cancer, radical trachelectomy preserves fertility, leading to a good rate of living newborns without impairing the chances of survival.

Publication types

  • English Abstract

MeSH terms

  • Abortion, Spontaneous / epidemiology
  • Adult
  • Female
  • Fertility*
  • Gynecologic Surgical Procedures*
  • Humans
  • Neoplasm Recurrence, Local
  • Neoplasm Staging
  • Pregnancy
  • Pregnancy Outcome
  • Uterine Cervical Neoplasms / pathology*
  • Uterine Cervical Neoplasms / surgery*