Use of pyrosequencing to detect clinically relevant polymorphisms in dihydropyrimidine dehydrogenase

Clin Chem. 2003 Oct;49(10):1661-4. doi: 10.1373/49.10.1661.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • African Continental Ancestry Group / genetics*
  • Chromosomes, Human, Pair 20
  • Dihydrouracil Dehydrogenase (NADP)
  • European Continental Ancestry Group / genetics*
  • Fluorouracil / metabolism
  • Gene Frequency
  • Genotype
  • Humans
  • Inactivation, Metabolic / genetics
  • Oxidoreductases / genetics*
  • Polymorphism, Single Nucleotide / genetics*
  • Sequence Analysis, DNA / methods*

Substances

  • Oxidoreductases
  • Dihydrouracil Dehydrogenase (NADP)
  • Fluorouracil