The Saintly Side of Smac/DIABLO: Giving Anticancer Drug-Induced Apoptosis a Boost

Cell Death Differ. 2003 Oct;10(10):1118-20. doi: 10.1038/sj.cdd.4401294.

Publication types

  • News
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Apoptosis / drug effects*
  • Apoptosis / physiology
  • Apoptosis Regulatory Proteins
  • Carrier Proteins / chemistry
  • Carrier Proteins / physiology*
  • Caspases / metabolism
  • Cytochromes c / metabolism
  • Humans
  • Inhibitor of Apoptosis Proteins
  • Intracellular Signaling Peptides and Proteins
  • Mitochondria / physiology
  • Mitochondrial Proteins / chemistry
  • Mitochondrial Proteins / physiology*
  • Models, Biological
  • Neoplasms / drug therapy*
  • Peptides / therapeutic use*
  • Proteins / metabolism
  • Signal Transduction / physiology
  • X-Linked Inhibitor of Apoptosis Protein

Substances

  • Apoptosis Regulatory Proteins
  • Carrier Proteins
  • DIABLO protein, human
  • Inhibitor of Apoptosis Proteins
  • Intracellular Signaling Peptides and Proteins
  • Mitochondrial Proteins
  • Peptides
  • Proteins
  • X-Linked Inhibitor of Apoptosis Protein
  • XIAP protein, human
  • Cytochromes c
  • Caspases