Erythromycin esterase gene ere(A) is located in a functional gene cassette in an unusual class 2 integron

Antimicrob Agents Chemother. 2003 Oct;47(10):3326-31. doi: 10.1128/AAC.47.10.3326-3331.2003.

Abstract

The gene ere(A) of the plasmid pIP1100 is larger than originally reported and is organized as an integron gene cassette. The ere(A) gene cassette carries its own promoter and is propagated by a class 2 integron with an insertion sequence element, IS1, inserted upstream of the intI2 gene. The mobility of the ere(A) cassette has been demonstrated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Amino Acid Sequence
  • Base Sequence
  • Binding Sites
  • Carboxylic Ester Hydrolases / genetics*
  • Chromosome Mapping
  • DNA Transposable Elements / genetics
  • DNA, Bacterial / genetics
  • Drug Resistance, Bacterial / genetics
  • Escherichia coli / enzymology
  • Escherichia coli / genetics
  • Integrons / genetics*
  • Microbial Sensitivity Tests
  • Molecular Sequence Data
  • Phenotype
  • Plasmids / genetics
  • Providencia / enzymology
  • Providencia / genetics
  • Recombination, Genetic

Substances

  • DNA Transposable Elements
  • DNA, Bacterial
  • Carboxylic Ester Hydrolases
  • erythromycin esterase

Associated data

  • GENBANK/AY183453