Familial hollow visceral myopathy with varying urological manifestations

Br J Urol. 1992 Oct;70(4):435-8. doi: 10.1111/j.1464-410x.1992.tb15804.x.


A family with hereditary hollow visceral myopathy is described, with characteristic variation in expression between affected members. Very severe and widespread involvement of the gastrointestinal and urinary tracts in 1 patient contrasted with isolated urinary tract involvement in 2 others, and it is suggested that hollow visceral myopathy should be considered in the differential diagnosis of primary detrusor failure. The management of urinary tract involvement is discussed and a conservative approach is recommended.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Family Health
  • Female
  • Humans
  • Intestinal Pseudo-Obstruction / complications
  • Intestinal Pseudo-Obstruction / genetics*
  • Male
  • Middle Aged
  • Muscle, Smooth / abnormalities*
  • Urologic Diseases / complications
  • Urologic Diseases / genetics*
  • Urologic Diseases / therapy