Quetiapine treatment in a patient with Tourette's syndrome, obsessive-compulsive disorder and drug-induced mania

Isr J Psychiatry Relat Sci. 2003;40(2):150-2.


A young man with a 13 year history of Tourette disorder and obsessive-compulsive disorder developed mania on clomipramine. Quetiapine 600 mg, daily was followed by resolution of the mania and improvement of the symptoms of Tourette disorder and obsessive compulsive disorder. It seems that quetiapine may be useful in treatment of Tourette disorder with or without comorbid disorders.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antipsychotic Agents / therapeutic use*
  • Bipolar Disorder / chemically induced*
  • Bipolar Disorder / drug therapy*
  • Clomipramine / adverse effects*
  • Dibenzothiazepines / therapeutic use*
  • Humans
  • Male
  • Obsessive-Compulsive Disorder / drug therapy*
  • Quetiapine Fumarate
  • Serotonin Uptake Inhibitors / adverse effects*
  • Tourette Syndrome / drug therapy*


  • Antipsychotic Agents
  • Dibenzothiazepines
  • Serotonin Uptake Inhibitors
  • Quetiapine Fumarate
  • Clomipramine