Communication in neuronal networks

Science. 2003 Sep 26;301(5641):1870-4. doi: 10.1126/science.1089662.


Brains perform with remarkable efficiency, are capable of prodigious computation, and are marvels of communication. We are beginning to understand some of the geometric, biophysical, and energy constraints that have governed the evolution of cortical networks. To operate efficiently within these constraints, nature has optimized the structure and function of cortical networks with design principles similar to those used in electronic networks. The brain also exploits the adaptability of biological systems to reconfigure in response to changing needs.

Publication types

  • Review

MeSH terms

  • Action Potentials
  • Animals
  • Biological Evolution
  • Brain / physiology*
  • Cell Communication*
  • Humans
  • Nerve Net / physiology*
  • Neuronal Plasticity*
  • Neurons / physiology*
  • Synaptic Transmission*