Purpose: To describe an unusual case of an inflammatory scleral nodule associated with systemic sarcoidosis.
Design: Observational case report.
Methods: A patient presented with a red, painful, elevated scleral nodule on the left eye that was unresponsive to nonsteroidal anti-inflammatory drugs and topical corticosteroids.
Results: Laboratory evaluation was normal with the exception of elevated liver function tests. Further evaluation by a gastroenterologist revealed a granulomatous hepatitis secondary to sarcoidosis, which was confirmed by liver biopsy. Treatment with oral prednisone resulted in resolution of the hepatitis and scleral nodule. The patient has been recurrence-free over 7 months of follow-up.
Conclusion: Although rare, scleral disease may be associated with sarcoidosis.