Percutaneous coronary intervention versus fibrinolytic therapy in acute myocardial infarction: is timing (almost) everything?

Am J Cardiol. 2003 Oct 1;92(7):824-6. doi: 10.1016/s0002-9149(03)00891-9.


The mortality benefit associated with primary percutaneous coronary intervention in ST-segment elevation myocardial infarction may be lost if door-to-balloon time is delayed by >1 hour as compared with fibrinolytic therapy door-to-needle time. Interventional cardiology laboratories endeavoring to achieve the benefits of primary percutaneous coronary intervention seen in randomized clinical trials should aim to match their short door-to-balloon times.

Publication types

  • Comparative Study

MeSH terms

  • Angioplasty, Balloon, Coronary / statistics & numerical data*
  • Humans
  • Linear Models
  • Myocardial Infarction / complications
  • Myocardial Infarction / therapy*
  • Recurrence
  • Stroke / complications
  • Survival Analysis
  • Thrombolytic Therapy / statistics & numerical data*
  • Time Factors
  • Treatment Outcome