Colorectal cancer, screening and survival: the influence of socio-economic deprivation

Public Health. 2003 Nov;117(6):389-95. doi: 10.1016/S0033-3506(03)00146-X.


Objectives: To determine the extent to which socio-economic deprivation explains colorectal cancer prevalence, subject participation in screening, and postoperative survival and life expectancy.

Methods: Regression analyses of clinical data from a large randomized controlled trial, augmented by geographical-based indices of deprivation.

Results: Deprivation appears to exert no significant impact on colorectal cancer prevalence but is a major factor explaining subject participation in screening. Cancer detection at later stages reduces life expectancy at time of treatment. Females from more-deprived areas have poorer post-treatment life expectancies and survival prospects, independently of their screening behaviour.

Conclusions: Screening increases the chances of having a cancer treated at an earlier stage, and treatment at an earlier stage is associated with longer subsequent life expectancy. However, those from more-deprived areas are less likely to accept an invitation to be screened.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Colorectal Neoplasms / diagnosis*
  • Colorectal Neoplasms / economics
  • Colorectal Neoplasms / mortality*
  • Databases as Topic
  • England / epidemiology
  • Family Practice
  • Female
  • Humans
  • Life Expectancy
  • Male
  • Mass Screening / statistics & numerical data*
  • Middle Aged
  • Poverty / statistics & numerical data*
  • Prevalence
  • Proportional Hazards Models
  • Social Class*
  • Socioeconomic Factors
  • Survival Analysis*
  • Treatment Outcome
  • Vulnerable Populations / statistics & numerical data*