Sporostatic effect of some oils against fungi causing otomycosis

Indian J Med Sci. 1992 Jan;46(1):1-6.


In vitro animycotic effect of mustard, groundnut, soybean, coconut and amla oils on five fungi i.e., Aspergillus niger, A. flavus, Absidia corymbifera, Penicillium nigricans and Candida albicans isolated from otitic fungal infection of external ear (Tympanic membrane) of human being was studied. Spore germination was evaluated in the oil samples as such after heating for two minutes & after boiling the oil. Data show that mustard and coconut oil seem to be effective as in these the spore germination was poor. Other oils were not found to be much effective. Sporostatic effect was noted only when the oils were used after heating or boiling this may be correlated by the synthesis of enzymes during spore germination.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifungal Agents / administration & dosage*
  • Fungi / drug effects
  • Humans
  • Microbial Sensitivity Tests
  • Mycoses / drug therapy*
  • Mycoses / microbiology
  • Otitis Media / drug therapy*
  • Otitis Media / microbiology
  • Plant Oils / administration & dosage*
  • Spores, Fungal / drug effects


  • Antifungal Agents
  • Plant Oils