A review of low-carbohydrate ketogenic diets

Curr Atheroscler Rep. 2003 Nov;5(6):476-83. doi: 10.1007/s11883-003-0038-6.


In response to the emerging epidemic of obesity in the United States, a renewal of interest in alternative diets has occurred, especially in diets that limit carbohydrate intake. Recent research has demonstrated that low-carbohydrate ketogenic diets can lead to weight loss and favorable changes in serum triglycerides and high-density lipoprotein cholesterol. This review summarizes the physiology and recent clinical studies regarding this type of diet.

Publication types

  • Review

MeSH terms

  • Cholesterol, HDL / blood
  • Clinical Trials as Topic
  • Diet, Reducing*
  • Dietary Carbohydrates / administration & dosage*
  • Humans
  • Ketone Bodies / biosynthesis*
  • Ketosis / blood
  • Ketosis / etiology
  • Obesity / blood
  • Obesity / diet therapy*
  • Treatment Outcome
  • Triglycerides / blood


  • Cholesterol, HDL
  • Dietary Carbohydrates
  • Ketone Bodies
  • Triglycerides