Abstract
This chapter addresses the increasing incidence of spinal haematoma after central neuraxis anaesthesia in patients receiving drugs that affect coagulation. Administration of low-molecular-weight heparins in the perioperative period is highlighted because these drugs remain the 'gold standard' for prophylaxis against deep-vein thrombosis. The performance of spinal anaesthesia in patients already receiving antiplatelet drugs is discussed--as well as special warnings in such a setting. In addition, issues such as those concerning the administration of unfractionated heparin, anti-vitamin K drugs or new antiplatelet and antithrombotic medications are addressed. Finally, specific recommendations regarding each class of drug are defined in order to avoid the occurrence of a rare but catastrophic event such as spinal haematoma.
MeSH terms
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Anesthesia, Spinal / adverse effects*
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Anticoagulants / administration & dosage
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Anticoagulants / adverse effects*
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Anticoagulants / therapeutic use
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Contraindications
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Fibrinolytic Agents / administration & dosage
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Fibrinolytic Agents / therapeutic use
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Hematoma, Subdural / chemically induced
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Hematoma, Subdural / etiology
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Hematoma, Subdural / prevention & control*
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Heparin / administration & dosage
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Heparin / therapeutic use
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Heparin, Low-Molecular-Weight / administration & dosage
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Heparin, Low-Molecular-Weight / therapeutic use
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Humans
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Platelet Aggregation Inhibitors / administration & dosage
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Platelet Aggregation Inhibitors / therapeutic use
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Risk Factors
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Warfarin / administration & dosage
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Warfarin / therapeutic use
Substances
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Anticoagulants
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Fibrinolytic Agents
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Heparin, Low-Molecular-Weight
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Platelet Aggregation Inhibitors
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Warfarin
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Heparin